Antidepressants Cause Weak and Brittle Bones

Researchers have known about the increased risk of osteoporosis in people taking SSRIs for years. They have also known that SSRIs concentrate in bones even more than they do in the brain. What they didn’t know until recently is how they cause osteoporosis. Now they do. SSRIs work by interfering with the actions of the neurotransmitter (brain chemical) called serotonin.


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Researchers Now Finding Connection Between Osteoporosis and Diabetes

Researchers are trying to determine how to stimulate osteoblasts to build bone rather than blocking osteoclasts. They’ve been investigating these cells more closely to determine exactly how they work. They’ve found that these cells rely heavily on a good supply of oxygenated blood. To determine just how dependent the bones are on this oxygen, the researchers analyzed mice that had genetically mutated bone cells. These cells function as though they have insufficient oxygen levels. The bones they generated were unusually heavy and absorbed quite a bit of glucose, increasing the risk of diabetes.


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Too Much Exercise May Exacerbate Back Pain

Researchers found that nearly half of the older adults they studied were getting a warning sign from their bodies that they were overdoing it in their exercise. And this was starting to take a toll: Their back pain was linked to less-efficient walking, reduced endurance, and ultimately to walking difficulties.


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