How much CoQ10 do you
need to treat heart failure?
You may know that I've long recommended CoQ10 for congestive heart failure (CHF). Most people take about 200 mg per day - about double the average daily dose - to treat CHF. But is that enough?

To determine the daily dose, we have to look at how the dose impacts your heart's ejection fraction. That's the percentage volume pumped out per beat. A normal heart's ejection fraction is 60+%. But sometimes that amount falls to below 30%. When you get below 25%, your life hangs in the balance. Any improvement, no matter how small, would be a terrific boon to your body.

A review of 11 CoQ10 studies has confirmed that a 3.7% improvement in ejection fraction and a 0.28 Liter/minute increase in heart output. In patients not taking ACE inhibitor drugs, the ejection fraction improvement was even greater at 6.74%. Dosage in the studies ranged from 60 mg per day to 200 mg per day.

It is a travesty that most conventional cardiologists still refuse to this nutrient. But even if they do, they're looking at these dosages, which isn't enough. The doses used in these studies, in my opinion, are too small. I use 300 mg-600 mg per day for conditions as serious as CHF. If you have CHF, be sure you take these doses.

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CoQ10 is a relatively expensive nutrient at these doses. But they are far more effective at boosting your heart's strength. You'll have to determine what you can afford. I continue to like and use the formulation provided by Advanced Bionutritionals. Their Ubiquinol CoQ10 is one of the best-absorbed brands on the market. Because it's so well absorbed, you need to take only half the dose (150-300 mg).

If you have any doubt about whether you're taking enough or not, get your blood level of CoQ10 checked to be sure that you are way over the top of the lab reference range. Here's one place where more is most likely better.

REF: “The impact of coenzyme Q10 on systolic function in patients with chronic heart failure,” Sander S, Coleman SI, et al, Journal of Cardiac Failure, 2006; 12(6): 464-72. (Address: University of Connecticut School of Pharmacy, Storrs, Connecticut 06269, USA).

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