One supplement stops eye problems and Raynaud’s

Dr. Frank Shallenberger, MD

July 25, 2022


One of the most aggravating conditions that can happen to anyone is Raynaud’s syndrome.

If you haven’t heard of Raynaud’s, you’ll be hearing more about it. That’s because it’s extremely common. Anywhere from 3-5% of the general population has the problem. And it gets as high as 15% in some women.

So if you have Raynaud’s don’t feel too bad. There are plenty of other people out there in the same situation.

And here’s some good news. It looks like for many people, there’s a simple, safe, and natural way to deal with Raynaud’s that might cut to the very core of what causes it.

And it can protect your vision as well.

Raynaud’s is a condition in which the blood vessels that supply the fingers, toes, and earlobes go into spasm. This causes a decrease in circulation.

The blood flow is often reduced so much that these areas appear pale or white, feel cold and numb, and frequently hurt. If it gets really bad, the areas start turning blue!

It’s similar to what happens to us all when these areas are exposed to severe cold. In fact, the thing that most often causes the attacks is exposure to cold. But in Raynaud’s even mildly cold temperatures can cause the reaction.

The most common treatment is to immediately warm the areas to help bring back the blood flow.

Raynaud’s comes in two flavors. The most common is what we call primary Raynaud’s. Primary Raynaud’s is rarely serious. Fortunately, more than 95% of Raynaud’s cases are the primary form.

The other kind is the secondary form. This form is associated with certain autoimmune diseases such as rheumatoid arthritis, scleroderma, and lupus.

The cause of Raynaud’s is not fully known. And for different people, there may be different causes.

But a recent review article on Raynaud’s points out that studies have found that people with both forms of Raynaud’s are deficient in nitric oxide.

This makes sense. I’ve told you in the past that nitric oxide is what the body uses to open up blood vessels. It prevents them from going into a spasm and keeps the blood flowing.

A deficiency of nitric oxide plays a major role in what causes Raynaud’s. And to back that up, there’s a very interesting report of four cases of the most severe form of Raynaud’s that responded to nitric oxide therapy.

The authors reported on the use of l-arginine to treat Raynaud’s. They were specifically looking at cases of Raynaud’s that were severe enough to cause actual destruction of the finger tissue called necrosis.

This is so serious that it can result in a loss of the fingers. Fortunately, cases this severe are rare. They used it because, as I’ve told you before, l-arginine stimulates the production of nitric oxide, especially in the young. The results were amazing.

Using l-arginine, the doctors completely reversed two cases of necrosis and saved their patients’ fingers. They also described two other cases in which the symptoms of severe Raynaud’s were not eliminated, but did significantly improve with l-arginine.

Another case comes from an optometrist. He recently saw a 52-year-old woman whom he had known for many years.

During the course of his examination, he used a test strip to determine her level of nitric oxide. When she turned up deficient, he told her that he thought it would be a good idea for her to start taking a supplement called CircO2.

CircO2 is a potent stimulator of nitric oxide production. And it was his opinion that it would help protect her vision as she grew older.

At the same time, he noticed that her hands were cherry-purple in color. He knew that she was a wine distributor. So when he saw her hands, he asked if she was crushing grapes with her fingers. She told him no, the discoloration was from Raynaud’s. She had been suffering from it for over 20 years.

She then left the office with his recommendation to take a CircO2 lozenge twice a day for her eyes. Well, you can probably guess what happened next.

Here are his words, “She returned today, close to tears, and stated she has not experienced hand pain for the first time in many, many years. When I further questioned her, she said that she had been getting Raynaud’s symptoms many times a week for as long as she can remember. On a scale of 0 -10, 10 being the worst, her hand pain has been an 8 in the winter and a 3-5 in the summer. But since she had been taking CircO2 she rated her symptoms at zero!”

I do not know if everyone with Raynaud’s will have results this good from CircO2. But I have to say that if I had the problem, I would definitely give it a try. Try taking one lozenge two to three times a day for four to six weeks.

And don’t use antibacterial mouthwash or antacid pills because these can inhibit nitric oxide formation.

You also can try l-arginine. I would suggest about 3 grams (3,000 mg), two times daily. But don’t forget that there are many times in which CircO2 will work when l-arginine won’t, especially in older people.


Baumhäkel, M. and M. Böhm. “Recent achievements in the management of Raynaud’s phenomenon. Vasc Health Risk Manag. 2010 April 15;6:207-14.
Rembold, C.M. and C.R. Ayers. “Oral L-arginine can reverse digital necrosis in Raynaud’s phenomenon.” Mol Cell Biochem. 2003 February;244(1-2):139-41.

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