Polyphenol Treatments Slow Inflammation

Volume 14    |   Issue 48

By now, most everybody who is paying attention knows that uncontrolled and/or excessive inflammation is damaging to the body and leads to chronic disease. One good way to measure the inflammation in your body is with an inexpensive and very common blood test called the hs-CRP (highly sensitive C-reactive protein). The normal range for hs-CRP is less than 3 mg/L. But the healthiest level of inflammation yields an hs-CRP less than 1 mg/L. So please have your doctor check this test at least once a year. And if it's consistently more than 1 mg/L, it's in your best interest to do something to bring it down. Here's what you can do.

Polyphenols are a class of compounds that abound in fruits and vegetables. And a recent study shows how having a diet high in polyphenols might be one of the best ways to reduce inflammation.

The researchers looked at the effect of various polyphenols on the way our lymphocytes release cytokines. Lymphocytes are cells that control the immune system. When your immune system activates them, they release messenger molecules called cytokines. And many of these cytokines create inflammation. So, what the researchers did was to evaluate whether or not specific polyphenols and polyphenol mixtures would be able to decrease the inflammatory cytokine effect from activated lymphocytes. Here's what they found.

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They compared 31 polyphenols and six polyphenol mixtures for effects on pro-inflammatory cytokine release by lymphocytes. They found that the following polyphenols were especially effective at reducing the inflammatory response: resveratrol, isorhamnetin, curcumin, vanillic acid, and certain specific polyphenol mixtures. These are exactly the same kinds of polyphenols that are commonly found in spices, onions, turmeric, red grapes, green tea, coffee, chocolate, and acai berries.

If you find that your hs-CRP is high, please take it seriously even if you feel great. Inflammation is like rust. You might not notice it, but it never sleeps and is always working to break things down. Make sure you eat an abundance of the foods and spices so high in polyphenols. And as an addition, consider taking two tablets every day of Reduloxin. This is a supplement that is highly concentrated in many of these polyphenols and helps control inflammation.

Yours for better health,






Ford CT, Richardson S, et al. Identification of (poly)phenol treatments that modulate the release of pro-inflammatory cytokines by human lymphocytes. Br J Nutr. 2016 May 28;115(10):1699-710.

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