As you may know, resveratrol is a plant-based polyphenol that's celebrated for its ability to protect your health, doing everything from boosting immunity to lowering your risk of cardiovascular disease. Researchers also have studied it in relation to dementia, particularly to Alzheimer's disease. But until recently, the results were rather inconclusive. However, since Alzheimer's is currently considered incurable and resveratrol has shown so much potential, researchers continued to investigate whether it could help after all. And it's a good thing they did.
What stands out about this study is how much you have to take to see results for Alzheimer's. Many health experts have said for years that you don't need to take resveratrol supplements because you can get enough of it from foods like grapes, pomegranates, and even red wine. While those foods do contain resveratrol, they don't have enough to help Alzheimer's patients. However, a study published in the journal Neurology found that resveratrol can be beneficial — you just have to take a lot of it.
For this study, the researchers divided 119 participants with mild to moderate Alzheimer's into two groups. One group received a placebo, while the other group started with 500 mg of resveratrol per day and worked their way up to 1,000 mg twice a day. The researchers found two important things. First, the resveratrol mimicked the effects of calorie restriction, which has been shown to delay and even prevent Alzheimer's in the long term.
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They also found that resveratrol helps move amyloid-beta plaques out of the brain and decreases brain inflammation. A follow-up study found that high levels of resveratrol (the amount found in 1,000 bottles of red wine) helped keep proteins that can break down the blood-brain barrier out of the brain. Although the resveratrol did cause some side effects, including nausea, diarrhea, and weight changes, in some of the participants, they were a small price to pay for the brain-defense benefits the participants received.
If you want to prevent Alzheimer's, you need to take in quite a bit of resveratrol. A glass of red wine or a handful of grapes won't cut it (though these are fine if you enjoy them). And no, you don't need to try to see how quickly you can make your way through 1,000 bottles of red wine. But you can take Advanced Polyphenol Formula. It will give you much more resveratrol than you can get from your diet alone, in addition to several other beneficial polyphenols to protect your brain and your mitochondrial function.
Yours for better health,
Frank Shallenberger, MD