Volume 12, Issue 51
Why you shouldn’t be taking l-arginine
Are you taking large doses of l-arginine to increase your nitric oxide production? I hope not. If you are, I have some bad news for you. It doesn't work.

I have talked about nitric oxide many times before. It is one of the most critical oxygen-based molecules that you have in your body. Nitric oxide regulates blood pressure, blood vessel function, sexual function, and immune function. People with atherosclerosis, high blood pressure, cardiovascular disease, strokes, and diabetes typically have insufficient levels of nitric oxide. So what's all this got to do with l-arginine?

L-arginine is an amino acid. That means that it's a component of the proteins in your diet. But the thing about l-arginine is that your body can convert it to nitric oxide. But your body also can convert it into another amino acid called urea. Despite the urea conversion, many doctors have prescribed fairly large doses of l-arginine for the above mentioned nitric oxide deficiency diseases. They're hoping that your body will convert some of it into nitric oxide. I used to be one of those doctors. I eventually stopped because the truth was that it just did not work as advertised. And now a recent study shows why.

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The researchers studied nine healthy men and women. They gave all of them various doses of l-arginine. Then they used a special technique to determine how much of the l-arginine went into nitric oxide production and how much was converted to urea. The results are pretty dismal for all those who had hoped that the l-arginine they were taking was converted to nitric oxide.

In every case, after the participants ingested and absorbed the l-arginine, 60% of it was immediately converted to urea in the liver. Of the remaining l-arginine that made it to the blood stream, only around 2% went to nitric oxide production. All in all, that's a miniscule amount. Less than one-tenth of 1% of the l-arginine that the subjects took was converted to nitric oxide. So if you are looking to increase your levels of nitric oxide, you can forget about doing it with l-arginine. But that is not the end of the story.

There is a supplement that can increase your nitric oxide levels. And you can get it at www.advancedbionutritionals.com. It's called CircO2. Just take one lozenge twice a day. One particular study shows that within one hour, your nitric oxide levels will be higher and your blood pressure lower. I call that amazing. How does it work? In a very ingenious and patented process. It works independently of l-arginine by causing nitrate and nitrite to be converted into nitric oxide.

So if you are taking l-arginine hoping to have the benefits of higher nitric oxide production, you can stop now. And instead take CircO2.

Yours for better health,

Mariotti F, Petzke KJ, Bonnet D, et al. Kinetics of the utilization of dietary arginine for nitric oxide and urea synthesis: insight into the arginine-nitric oxide metabolic system in humans. Am J Clin Nutr. 2013 May;97(5):972-9.

Houston M, Hays L. Acute effects of an oral nitric oxide supplement on blood pressure, endothelial function, and vascular compliance in hypertensive patients. J Clin Hypertens (Greenwich). 2014 Jul;16(7):524-9.

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