Volume 2, Issue 48
November 26, 2009
Decrease Your Chances of Cancer With This Supplement
Medicine already knows that conventional chemotherapy treatments for cancer are a failure. Unless you have some testicular cancers or some lymphomas, research and experience have proven that chemo doesn't work. But there's hope. If you have cancer - or just want to prevent it — there's a natural treatment you can use to fight this killer.
Researchers have proven that the fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) will prevent cancer. And your best source of EPA and DHA is in fish oil. We know that fish oil works particularly well against colon, breast, and prostate cancers. But new research suggests that fish oil has profound anti-cancer capabilities in patients who already have cancer!
These studies show that EPA and DHA reduce the inflammation associated with cancer. And they also act to slow cancer growth and spread.
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One of the most powerful aspects of fish oil is that it's anti-angiogenic. This means it inhibits the growth of the new blood vessels. Cancers must have an ever increasing supply of blood in order to survive. And they use the process of angiogenesis to cause the body to grow new blood vessels to service them.
Tumors manufacture special messenger molecules called angiogenic mediators to kick-start angiogenesis. Then they release these molecules into the surrounding tissues where they stimulate the body to create the much needed new blood vessels. The European Journal of Cancer recently published a review article with details on how EPA and DHA inhibit these angiogenesis mediators.
I've treated many cases of cancer. And I can tell you that inhibiting these angeogenic mediators is often a critical aspect of successfully controlling cancer.
For example, one of the most effective ways to treat colon and rectal cancers is with a drug called bevacizumab (Avastin). Bevacizumab works by blocking the effects of Vascular Endothelial Growth Factor (VEGF), one of the angiogenic mediators that fish oil also blocks.
Another drug, imatinib (known as Gleevec), is often effective in treating certain leukemias and gastrointestinal cancers. Imatinib is a potent inhibitor of Platelet-Derived Growth Factor (PDGF), again one of the mediators that fish oil blocks.
Another effective class of drugs that reduce the chance of getting cancer, particularly colon cancer, is the COX-2 inhibitors. Examples of COX-2 inhibitors are aspirin and ibuprofen. One COX-2 inhibitor, rofecoxib (you know it as Vioxx), causes cardiac death in some patients. Once again, the studies show that EPA and DHA are natural COX-2 inhibitors that have no side effects, plus they have all of the other additional anti-angiogenic properties mentioned above.
Finally, one of the serious risks that many cancer patients face is the risk of life-threatening blood clots. EPA and DHA are also potent inhibitors of blood clots. They do this by inhibiting both the activation and the aggregation of platelets. Platelets are blood components that are often over-activated in cancer patients. They are responsible for the increased blood-clot risk.
Whether you already have cancer or you simply want to prevent it, there's probably nothing you can take that would be more effective than a good dose of EPA and DHA. For most people, I would recommend about 500 mg of each per day. If you have cancer, I often recommend up to 10 times this amount. Be sure to talk it over with your doctor if you are thinking about taking this larger amount.
Finding your Real Cures,
Frank Shallenberger, MD
Spencer L, Mann C, Metcalfe M, et al.ÿ The effect of omega-3 FAs on tumour angiogenesis and their therapeutic potential. Eur J Cancer. 2009 August;45(12):2077-86. Epub 2009 June 1.
Copyright 2009 Soundview Publishing, LLC
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